Target：FAM111B

Gene Name：FAM111B

Protein Name：Protein FAM111B

Human Gene Id：374393

Human Swiss Prot No：Q6SJ93

Immunogen：The antiserum was produced against synthesized peptide derived from human F111B. AA range:281-330

Specificity：FAM111B Polyclonal Antibody detects endogenous levels of FAM111B protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:200. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FAM111B;CANP;Protein FAM111B;Cancer-associated nucleoprotein

Molecular Weight(Da)：85kD

Background： This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014],

Function：sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the FAM111 family.,

Expression：Widely expressed.