Target:ETAA1
Gene Name:ETAA1 ETAA16
Protein Name:Ewing's tumor-associated antigen 1 (Ewing's tumor-associated antigen 16)
Human Gene Id:54465
Human Swiss Prot No:Q9NY74
Mouse Swiss Prot No:Q5SVT3
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:ETAA1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):101kD
Background:PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,tissue specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.,
Function:PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,tissue specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.,
Subcellular Location:Nucleus . Localizes at sites of DNA damage following replication stress (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex (PubMed:27601467, PubMed:27723720). .
Expression:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.