Target：NPY5-R

Fields：Neuroactive ligand-receptor interaction

Gene Name：NPY5R

Protein Name：Neuropeptide Y receptor type 5

Human Gene Id：4889

Human Swiss Prot No：Q15761

Mouse Gene Id：18168

Mouse Swiss Prot No：O70342

Rat Gene Id：25340

Rat Swiss Prot No：Q63634

Immunogen：The antiserum was produced against synthesized peptide derived from human NPY5R. AA range:221-270

Specificity：NPY5-R Polyclonal Antibody detects endogenous levels of NPY5-R protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NPY5R;NPYR5;Neuropeptide Y receptor type 5;NPY5-R;NPY-Y5 receptor;NPYY5-R;Y5 receptor

Observed Band(KD)：48kD

Background： The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015],

Function：function:Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Brain; hypothalamus.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Brain; hypothalamus.