Target：NOP56

Fields：Ribosome biogenesis in eukaryotes;Spinocerebellar ataxia

Gene Name：NOP56

Protein Name：NOP56

Human Gene Id：10528

Human Swiss Prot No：O00567

Mouse Gene Id：67134

Mouse Swiss Prot No：Q9D6Z1

Immunogen：Synthesized peptide derived from NOP56 at AA range: 191-240

Specificity：NOP56 Polyclonal Antibody detects endogenous levels of NOP56

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：Nucleolar protein 56 (Nucleolar protein 5A)

Observed Band(KD)：65kD

Background： Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016],

Function：function:Required for 60S ribosomal subunit biogenesis.,similarity:Belongs to the NOP5/NOP56 family.,similarity:Contains 1 Nop domain.,subunit:Interacts with NOP1 and NOP58.,

Subcellular Location：Nucleus, nucleolus . Cytoplasm . Nucleus, nucleoplasm .

Expression： Brain,Cervix carcinoma,Epithelium,Uterus,