Target：NOCT

Gene Name：CCRN4L CCR4 NOC

Protein Name：Nocturnin (CCR4 protein homolog)

Human Gene Id：25819

Human Swiss Prot No：Q9UK39

Mouse Swiss Prot No：O35710

Rat Swiss Prot No：Q9ET55

Immunogen：Synthesized peptide derived from human protein . at AA range: 100-180

Specificity：NOCT Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：47kD

Background：nocturnin(NOCT) Homo sapiens The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008],

Function：function:Component of the circadian clock or downstream effector of clock function. Exhibits a high amplitude circadian rhythm with maximal levels in early evening. In constant darkness or constant light, the amplitude of the rhythm decreases.,similarity:Belongs to the CCR4/nocturin family.,

Subcellular Location：Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Mitochondrion .

Expression：Adipose tissue. Expression is higher in subcutaneous adipose tissue as compared to visceral adipose tissue.