Target：NGAP

Fields：Ras signaling pathway

Gene Name：RASAL2 NGAP

Protein Name：Ras GTPase-activating protein nGAP (RAS protein activator-like 2)

Human Gene Id：9462

Human Swiss Prot No：Q9UJF2

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：NGAP Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：125kD

Background： This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Function：function:Inhibitory regulator of the Ras-cyclic AMP pathway.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GAP domain.,

Subcellular Location：cytoplasm,cytosol,intrinsic component of the cytoplasmic side of the plasma membrane,

Expression： Brain,Epithelium,Heart,Muscle,PCR rescued clones,Peripheral Nervous System,