Target：NFATc2IP

Gene Name：NFATC2IP

Protein Name：NFATC2-interacting protein

Human Gene Id：84901

Human Swiss Prot No：Q8NCF5

Mouse Swiss Prot No：O09130

Immunogen：The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200

Specificity：NFATc2IP Polyclonal Antibody detects endogenous levels of NFATc2IP protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NFATC2IP;NIP45;NFATC2-interacting protein;45 kDa NF-AT-interacting protein;45 kDa NFAT-interacting protein;Nuclear factor of activated T-cells; cytoplasmic 2-interacting protein

Observed Band(KD)：48kD

Background：function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.,

Function：function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.,

Subcellular Location：Nucleus . Cytoplasm . TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. .

Expression： Brain,Epithelium,Eye,Liver,