Target：NF-1

Gene Name：NFIA

Protein Name：Nuclear factor 1 A-type

Human Gene Id：4774/4781/4782/4784

Human Swiss Prot No：Q12857/O00712/P08651/Q14938

Mouse Gene Id：18027/18028/18029/18032

Rat Gene Id：25492

Rat Swiss Prot No：P09414

Immunogen：The antiserum was produced against synthesized peptide derived from human Nuclear Factor 1. AA range:11-60

Specificity：NF-1 Polyclonal Antibody detects endogenous levels of NF-1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NFIA;KIAA1439;Nuclear factor 1 A-type;NF1-A;Nuclear factor 1/A;CCAAT-box-binding transcription factor;CTF;Nuclear factor I/A;NF-I/A;NFI-A;TGGCA-binding protein;NFIB;Nuclear factor 1 B-type;NF1-B;Nuclear factor 1/B;CCAAT-box-b

Observed Band(KD)：55kD

Background： This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Function：function:Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CTF/NF-I family.,similarity:Contains 1 CTF/NF-I DNA-binding domain.,subunit:Binds DNA as a homodimer.,

Subcellular Location：Nucleus.

Expression： Brain,Epithelium,Skeletal muscle,Testis,