Target：Neurotensin
Fields：Neuroactive ligand-receptor interaction
Gene Name：NTS
Protein Name：Neurotensin/neuromedin N
Human Gene Id：4922
Human Swiss Prot No：P30990
Mouse Gene Id：67405
Mouse Swiss Prot No：Q9D3P9
Rat Swiss Prot No：P20068
Immunogen：The antiserum was produced against synthesized peptide derived from the C-terminal region of human NTS. AA range:121-170
Specificity：Neurotensin Polyclonal Antibody detects endogenous levels of Neurotensin protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：NTS;Neurotensin/neuromedin N
Observed Band(KD)：20kD
Background： This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014],
Function：function:Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.,online information:Neurotensin entry,similarity:Belongs to the neurotensin family.,subcellular location:Packaged within secretory vesicles.,
Subcellular Location：Secreted. Cytoplasmic vesicle, secretory vesicle. Packaged within secretory vesicles.
Expression： Brain,Tongue,
