Target：Neuroglycan C

Gene Name：CSPG5

Protein Name：Chondroitin sulfate proteoglycan 5

Human Gene Id：10675

Human Swiss Prot No：O95196

Mouse Gene Id：29873

Mouse Swiss Prot No：Q71M36

Rat Gene Id：50568

Rat Swiss Prot No：Q9ERQ6

Immunogen：The antiserum was produced against synthesized peptide derived from human CSPG5. AA range:211-260

Specificity：Neuroglycan C Polyclonal Antibody detects endogenous levels of Neuroglycan C protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CSPG5;CALEB;NGC;Chondroitin sulfate proteoglycan 5;Acidic leucine-rich EGF-like domain-containing brain protein;Neuroglycan C

Observed Band(KD)：60kD

Background： The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],

Function：developmental stage:Expressed in brain of 3 months, 5 and 10-year-old individuals.,function:May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.,miscellaneous:Different forms of various molecular weight have been observed. Such forms are possibly due to different levels of glycosylation, phosphorylation and/or protein cleavage.,PTM:N-glycosylated.,PTM:O-glycosylated; contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissues maturation.,PTM:Phosphorylated; in intracellular and extracellular parts.,similarity:Contains 1 EGF-like domain.,subcellular location:In neurons, localizes to synaptic junctions (By similarity). Also detected in the endoplasmic reti

Subcellular Location：Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, synaptic cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cell surface . In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts. .

Expression：Restricted to brain (at protein level).