Target：NET4
Fields：Axon guidance
Gene Name：NTN4
Protein Name：Netrin-4 (Beta-netrin) (Hepar-derived netrin-like protein)
Human Gene Id：59277
Human Swiss Prot No：Q9HB63
Mouse Swiss Prot No：Q9JI33
Immunogen：Synthesized peptide derived from human protein . at AA range: 50-130
Specificity：NET4 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：69kD
Background： This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016],
Function：function:May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 1 NTR domain.,similarity:Contains 3 laminin EGF-like domains.,subcellular location:Major component.,subunit:May form a homodimer.,tissue specificity:Expressed in kidney, spleen, mammary gland, aorta, heart, ovary, prostate and fetal spleen.,
Subcellular Location：Secreted, extracellular space, extracellular matrix, basement membrane . Major component.
Expression：Expressed in kidney, spleen, mammary gland, aorta, heart, ovary, prostate and fetal spleen.
