Target:NEST
Gene Name:NES Nbla00170
Protein Name:Nestin
Human Gene Id:10763
Human Swiss Prot No:P48681
Mouse Swiss Prot No:Q6P5H2
Rat Swiss Prot No:P21263
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:NEST Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):178kD
Background: This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011],
Function:developmental stage:Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments.,function:May play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daughter cells during progenitor cell division.,similarity:Belongs to the intermediate filament family.,subunit:Interacts with FHOD3.,tissue specificity:CNS stem cells.,
Subcellular Location:cytoplasm,intermediate filament,extracellular matrix,intermediate filament cytoskeleton,
Expression:CNS stem cells.