Target：NCKX6

Gene Name：SLC24A6

Protein Name：Sodium/potassium/calcium exchanger 6

Human Gene Id：80024

Human Swiss Prot No：Q6J4K2

Mouse Swiss Prot No：Q925Q3

Immunogen：The antiserum was produced against synthesized peptide derived from human SLC24A6. AA range:494-543

Specificity：NCKX6 Polyclonal Antibody detects endogenous levels of NCKX6 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLC24A6;NCKX6;NCLX;Sodium/potassium/calcium exchanger 6;Na(+)/K(+)/Ca(2+)-exchange protein 6;Solute carrier family 24 member 6

Observed Band(KD)：60kD

Background： SLC24A6 belongs to a family of potassium-dependent sodium/calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion (Cai and Lytton, 2004 [PubMed 14625281]).[supplied by OMIM, Mar 2008],

Function：function:Transports Ca(2+) in exchange for either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+).,miscellaneous:Strongly inhibited by zinc.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,

Subcellular Location：Mitochondrion inner membrane ; Multi-pass membrane protein .

Expression：Present in pancreatic beta-cells (at protein level).