Target：NCKX3

Gene Name：SLC24A3

Protein Name：Sodium/potassium/calcium exchanger 3

Human Gene Id：57419

Human Swiss Prot No：Q9HC58

Mouse Swiss Prot No：Q99PD7

Rat Swiss Prot No：Q9EPQ0

Immunogen：The antiserum was produced against synthesized peptide derived from human SLC24A3. AA range:354-403

Specificity：NCKX3 Polyclonal Antibody detects endogenous levels of NCKX3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLC24A3;NCKX3;Sodium/potassium/calcium exchanger 3;Na(+)/K(+)/Ca(2+)-exchange protein 3;Solute carrier family 24 member 3

Observed Band(KD)：60kD

Background： Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008],

Function：function:Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,tissue specificity:Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Abundant in the brain (PubMed:11294880). Expressed at low levels in the aorta, uterus and intestine (PubMed:11294880).