Target：NBPF3

Gene Name：NBPF3 L7

Protein Name：Neuroblastoma breakpoint family member 3 (Protein AE2) (Protein SHIIIa4)

Human Gene Id：84224

Human Swiss Prot No：Q9H094

Immunogen：Synthesized peptide derived from human protein . at AA range: 410-490

Specificity：NBPF3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：69kD

Background：neuroblastoma breakpoint family member 3(NBPF3) Homo sapiens This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. DUF1220 copy number variations in human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene fami

Function：miscellaneous:Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.,similarity:Belongs to the NBPF family.,similarity:Contains 5 NBPF domains.,tissue specificity:Expressed in testis and fetal heart, as well as in non small cell lung carcinoma and neuroblastoma cell line.,

Subcellular Location：Cytoplasm .

Expression：Expressed in testis and fetal heart, as well as in non small cell lung carcinoma and neuroblastoma cell line.