Target：Nap1

Fields：RIG-I-like receptor signaling pathway

Gene Name：AZI2

Protein Name：5-azacytidine-induced protein 2

Human Gene Id：64343

Human Swiss Prot No：Q9H6S1

Mouse Gene Id：27215

Mouse Swiss Prot No：Q9QYP6

Rat Gene Id：316051

Rat Swiss Prot No：Q4KMA0

Immunogen：The antiserum was produced against synthesized peptide derived from human AZI2. AA range:10-59

Specificity：Nap1 Polyclonal Antibody detects endogenous levels of Nap1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：AZI2;NAP1;5-azacytidine-induced protein 2;NF-kappa-B-activating kinase-associated protein 1;Nak-associated protein 1;TILP

Observed Band(KD)：48kD

Background： AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008],

Function：function:Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1.,subunit:Interacts with IKBKE, TBK1 and TICAM1.,tissue specificity:Widely expressed. Abundant expression seen in the pancreas and testis.,

Subcellular Location：Cytoplasm .

Expression：Widely expressed (PubMed:14560022). Abundant expression seen in the pancreas and testis (PubMed:14560022).