Target：NADL2

Gene Name：NAALADL2

Protein Name：Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 (NAALADase L2)

Human Gene Id：254827

Human Swiss Prot No：Q58DX5

Immunogen：Synthesized peptide derived from human protein . at AA range: 190-270

Specificity：NADL2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：87kD

Background：caution:Although related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites.,function:May be catalytically inactive.,miscellaneous:The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, PubMed:15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.,sequence caution:Contaminating sequence at the C-terminus.,similarity:Belongs to the peptidase M28 family. M28B subfamily.,tissue specificity:Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.,

Function：caution:Although related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites.,function:May be catalytically inactive.,miscellaneous:The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, PubMed:15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.,sequence caution:Contaminating sequence at the C-terminus.,similarity:Belongs to the peptidase M28 family. M28B subfamily.,tissue specificity:Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.,

Subcellular Location：Membrane ; Single-pass type II membrane protein .

Expression：Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.