Target：MTF1

Gene Name：MTF1

Protein Name：Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1)

Human Gene Id：4520

Human Swiss Prot No：Q14872

Mouse Swiss Prot No：Q07243

Immunogen：Synthesized peptide derived from human protein . at AA range: 260-340

Specificity：MTF1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：82kD

Background： This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008],

Function：function:Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).,similarity:Contains 6 C2H2-type zinc fingers.,

Subcellular Location：Nucleus . Cytoplasm . Translocation to the nucleus is induced by metals. .

Expression： Liver,Muscle,