Target：MRP-L52

Gene Name：MRPL52

Protein Name：39S ribosomal protein L52 mitochondrial

Human Gene Id：122704

Human Swiss Prot No：Q86TS9

Mouse Swiss Prot No：Q9D0Y8

Immunogen：The antiserum was produced against synthesized peptide derived from human MRPL52. AA range:71-120

Specificity：MRP-L52 Polyclonal Antibody detects endogenous levels of MRP-L52 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MRPL52;39S ribosomal protein L52; mitochondrial;L52mt;MRP-L52

Molecular Weight(Da)：14kD

Background： Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which has no bacterial homolog. Multiple transcript variants encoding different protein isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008],

Function：subunit:Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.,

Subcellular Location：Mitochondrion .

Expression： Brain,Placenta,