Target:CD99
Fields:Cell adhesion molecules;Leukocyte transendothelial migration
Gene Name:CD99
Protein Name:CD99 antigen
Human Gene Id:4267
Human Swiss Prot No:P14209
Mouse Swiss Prot No:Q8VCN6
Immunogen:The antiserum was produced against synthesized peptide derived from human CD99. AA range:11-60
Specificity:MIC2 Polyclonal Antibody detects endogenous levels of MIC2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CD99;MIC2;MIC2X;MIC2Y;CD99 antigen;12E7;E2 antigen;Protein MIC2;T-cell surface glycoprotein E2;CD antigen CD99
Molecular Weight(Da):19kD
Background: The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016],
Function:function:Involved in T-cell adhesion processes. It is involved in spontaneous rosette formation with erythrocytes.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,PTM:Extensively O-glycosylated.,similarity:Belongs to the CD99 family.,
Subcellular Location:Membrane ; Single-pass type I membrane protein .
Expression: Brain,Kidney,Skin,T-cell,Uterus,