Target：ODC

Gene Name：SLC25A21

Protein Name：Mitochondrial 2-oxodicarboxylate carrier

Human Gene Id：89874

Human Swiss Prot No：Q9BQT8

Mouse Gene Id：217593

Mouse Swiss Prot No：Q8BZ09

Rat Gene Id：171151

Rat Swiss Prot No：Q99JD3

Immunogen：The antiserum was produced against synthesized peptide derived from human SLC25A21. AA range:134-183

Specificity：ODC Polyclonal Antibody detects endogenous levels of ODC protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLC25A21;ODC;Mitochondrial 2-oxodicarboxylate carrier;Solute carrier family 25 member 21

Observed Band(KD)：36kD

Background： SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004],

Function：function:Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,tissue specificity:Ubiquitous.,

Subcellular Location：Mitochondrion inner membrane; Multi-pass membrane protein.

Expression：Expressed in placenta, gall bladder and colon.