Target：OATP1

Fields：Bile secretion

Gene Name：SLCO1A2

Protein Name：Solute carrier organic anion transporter family member 1A2

Human Gene Id：6579

Human Swiss Prot No：P46721

Immunogen：The antiserum was produced against synthesized peptide derived from human SLCO1A2. AA range:251-300

Specificity：OATP1 Polyclonal Antibody detects endogenous levels of OATP1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLCO1A2;OATP;OATP1;OATP1A2;SLC21A3;Solute carrier organic anion transporter family member 1A2;OATP-A;Organic anion-transporting polypeptide 1;OATP-1;Sodium-independent organic anion transporter;Solute carrier family 21 member 3

Observed Band(KD)：80kD

Background： This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008],

Function：function:Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids.,similarity:Belongs to the organo anion transporter (TC 2.A.60) family.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression： Brain,Liver,Teratocarcinoma,