Target：PKI β

Gene Name：PKIB

Protein Name：cAMP-dependent protein kinase inhibitor beta

Human Gene Id：5570

Human Swiss Prot No：Q9C010

Mouse Swiss Prot No：Q04758

Rat Swiss Prot No：P27775

Immunogen：The antiserum was produced against synthesized peptide derived from human IPKB. AA range:29-78

Specificity：PKI β Polyclonal Antibody detects endogenous levels of PKI β protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000,WB 1:500-2000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PKIB;PRKACN2;cAMP-dependent protein kinase inhibitor beta;PKI-beta

Molecular Weight(Da)：8kD

Background：protein kinase (cAMP-dependent, catalytic) inhibitor beta(PKIB) Homo sapiens This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],

Function：function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,similarity:Belongs to the PKI family.,

Subcellular Location：nucleus,cytoplasm,

Expression： Placenta,