Target：Nup160

Fields：Nucleocytoplasmic transport;Amyotrophic lateral sclerosis

Gene Name：NUP160

Protein Name：Nuclear pore complex protein Nup160

Human Gene Id：23279

Human Swiss Prot No：Q12769

Mouse Gene Id：59015

Mouse Swiss Prot No：Q9Z0W3

Immunogen：The antiserum was produced against synthesized peptide derived from human NUP160. AA range:392-441

Specificity：Nup160 Polyclonal Antibody detects endogenous levels of Nup160 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NUP160;KIAA0197;NUP120;Nuclear pore complex protein Nup160;160 kDa nucleoporin;Nucleoporin Nup160

Observed Band(KD)：140kD

Background：nucleoporin 160(NUP160) Homo sapiens NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004],

Function：caution:It is uncertain whether Met-1 or Met-35 is the initiator.,function:Involved in poly(A)+ RNA transport.,sequence caution:Probable cloning artifact. Aberrant splice sites.,subunit:Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus.,

Subcellular Location：Nucleus, nuclear pore complex .

Expression： Bone marrow,Epithelium,Muscle,Skin,Small intestine,Testis,Trachea,