Target:NUFP1
Gene Name:NUFIP1
Protein Name:Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1)
Human Gene Id:26747
Human Swiss Prot No:Q9UHK0
Mouse Swiss Prot No:Q9QXX8
Rat Swiss Prot No:Q641W3
Immunogen:Synthesized peptide derived from human protein . at AA range: 180-260
Specificity:NUFP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):54kD
Background: This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012],
Function:function:Binds RNA.,similarity:Contains 1 C2H2-type zinc finger.,subcellular location:Distributed in the nucleus in a dot-like pattern.,subunit:Interacts with FMR1.,tissue specificity:Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.,
Subcellular Location:Nucleus . Distributed in the nucleus in a dot-like pattern.
Expression:Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.