Target：NUCKS

Gene Name：NUCKS1

Protein Name：Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

Human Gene Id：64710

Human Swiss Prot No：Q9H1E3

Mouse Gene Id：98415

Mouse Swiss Prot No：Q80XU3

Rat Gene Id：64709

Rat Swiss Prot No：Q9EPJ0

Immunogen：The antiserum was produced against synthesized peptide derived from human NUCKS1. AA range:28-77

Specificity：NUCKS Polyclonal Antibody detects endogenous levels of NUCKS protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NUCKS1;NUCKS;JC7;Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1;P1

Molecular Weight(Da)：27kD

Background： This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010],

Function：PTM:Phosphorylated by CDK1 and casein kinase. Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translated as Arg.,

Subcellular Location：Nucleus . Chromosome .

Expression：Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung.