Target:NTR1
Fields:Calcium signaling pathway;Neuroactive ligand-receptor interaction
Gene Name:NTSR1
Protein Name:Neurotensin receptor type 1
Human Gene Id:4923
Human Swiss Prot No:P30989
Mouse Gene Id:18216
Mouse Swiss Prot No:O88319
Immunogen:The antiserum was produced against synthesized peptide derived from human NTR1. AA range:181-230
Specificity:NTR1 Polyclonal Antibody detects endogenous levels of NTR1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NTSR1;NTRR;Neurotensin receptor type 1;NT-R-1;NTR1;High-affinity levocabastine-insensitive neurotensin receptor;NTRH
Observed Band(KD):46kD
Background: Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008],
Function:function:Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Neurotensin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Location:Cell membrane ; Multi-pass membrane protein . Membrane raft . Palmitoylation is required for localization at CAV1-enriched membrane rafts. .
Expression:Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.