Target：NSF

Fields：Synaptic vesicle cycle;GABAergic synapse;Vasopressin-regulated water reabsorption

Gene Name：NSF

Protein Name：Vesicle-fusing ATPase

Human Gene Id：4905

Human Swiss Prot No：P46459

Mouse Gene Id：18195

Mouse Swiss Prot No：P46460

Rat Gene Id：60355

Rat Swiss Prot No：Q9QUL6

Immunogen：Synthesized peptide derived from NSF . at AA range: 110-190

Specificity：NSF Polyclonal Antibody detects endogenous levels of NSF protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NSF;Vesicle-fusing ATPase;N-ethylmaleimide-sensitive fusion protein;NEM-sensitive fusion protein;Vesicular-fusion protein NSF

Observed Band(KD)：75kD

Background：catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.,similarity:Belongs to the AAA ATPase family.,subunit:Homohexamer. Interacts with GABARAP and GABARAPL2.,

Function：catalytic activity:ATP + H(2)O = ADP + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.,similarity:Belongs to the AAA ATPase family.,subunit:Homohexamer. Interacts with GABARAP and GABARAPL2.,

Subcellular Location：Cytoplasm.

Expression： Brain,Kidney,Lung,