Target：NRN1

Gene Name：NRN1 NRN

Protein Name：Neuritin

Human Gene Id：51299

Human Swiss Prot No：Q9NPD7

Mouse Swiss Prot No：Q8CFV4

Rat Swiss Prot No：O08957

Immunogen：Synthesized peptide derived from human protein . at AA range: 40-120

Specificity：NRN1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：15kD

Background： This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Function：function:Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.,similarity:Belongs to the neuritin family.,

Subcellular Location：Cell membrane ; Lipid-anchor, GPI-anchor . Cell junction, synapse .

Expression： Adrenal cortex,Brain,Uterus,