Target:NRK
Gene Name:NRK
Protein Name:Nik-related protein kinase (EC 2.7.11.1)
Human Gene Id:203447
Human Swiss Prot No:Q7Z2Y5
Mouse Swiss Prot No:Q9R0G8
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:NRK Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):174kD
Background:Nik related kinase(NRK) Homo sapiens The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010],
Function:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,
Subcellular Location:cytoplasm,integral component of membrane,
Expression: Fetal kidney,Ovary,Placenta,