Target：OTUB2

Gene Name：OTUB2

Protein Name：Ubiquitin thioesterase OTUB2

Human Gene Id：78990

Human Swiss Prot No：Q96DC9

Mouse Gene Id：68149

Mouse Swiss Prot No：Q9CQX0

Immunogen：The antiserum was produced against synthesized peptide derived from human OTUB2. AA range:133-182

Specificity：OTUB2 Polyclonal Antibody detects endogenous levels of OTUB2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：OTUB2;C14orf137;OTB2;OTU2;Ubiquitin thioesterase OTUB2;Deubiquitinating enzyme OTUB2;OTU domain-containing ubiquitin aldehyde-binding protein 2;Otubain-2;Ubiquitin-specific-processing protease OTUB2

Observed Band(KD)：27kD

Background：OTU deubiquitinase, ubiquitin aldehyde binding 2(OTUB2) Homo sapiens This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011],

Function：function:Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.,similarity:Belongs to the peptidase C65 family.,similarity:Contains 1 OTU domain.,tissue specificity:Widely expressed. Expressed at higher level in brain.,

Subcellular Location：nucleus,

Expression：Widely expressed. Expressed at higher level in brain.