Target:RhoBTB1/2
Fields:Ubiquitin mediated proteolysis
Gene Name:RHOBTB1/RHOBTB2
Protein Name:Rho-related BTB domain-containing protein 1/2
Human Gene Id:23221/9886
Human Swiss Prot No:O94844/Q9BYZ6
Mouse Gene Id:69288/246710
Immunogen:The antiserum was produced against synthesized peptide derived from human RHBT2. AA range:61-110
Specificity:RhoBTB1/2 Polyclonal Antibody detects endogenous levels of RhoBTB1/2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RHOBTB1;KIAA0740;Rho-related BTB domain-containing protein 1;RHOBTB2;DBC2;KIAA0717;Rho-related BTB domain-containing protein 2;Deleted in breast cancer 2 gene protein;p83
Observed Band(KD):83kD
Background: The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],
Function:similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.,
Subcellular Location:intracellular,cytosol,plasma membrane,
Expression:Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.