Target：P2RX4

Fields：Calcium signaling pathway;Neuroactive ligand-receptor interaction

Gene Name：P2RX4

Protein Name：P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor)

Human Gene Id：5025

Human Swiss Prot No：Q99571

Mouse Swiss Prot No：Q9JJX6

Rat Swiss Prot No：P51577

Immunogen：Synthesized peptide derived from human protein . at AA range: 150-230

Specificity：P2RX4 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：42kD

Background： The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012],

Function：function:Receptor for ATP that acts as a ligand gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.,online information:P2X receptor entry,similarity:Belongs to the P2X receptor family.,subunit:Homo- or heteropolymers.,

Subcellular Location：Membrane ; Multi-pass membrane protein .

Expression： Blood,Brain,Kidney,Liver,