Target：PABP3

Fields：mRNA surveillance pathway;RNA degradation

Gene Name：PABPC3

Protein Name：Polyadenylate-binding protein 3

Human Gene Id：5042

Human Swiss Prot No：Q9H361

Immunogen：The antiserum was produced against synthesized peptide derived from human PABPC3. AA range:352-401

Specificity：PABP3 Polyclonal Antibody detects endogenous levels of PABP3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000.IHC:1:50-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PABPC3;PABP3;PABPL3;Polyadenylate-binding protein 3;PABP-3;Poly(A)-binding protein 3;Testis-specific poly(A)-binding protein

Observed Band(KD)：70kD

Background： Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002],

Function：function:Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.,similarity:Belongs to the polyadenylate-binding protein type-1 family.,similarity:Contains 1 PABC domain.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Testis specific.,

Subcellular Location：Cytoplasm .

Expression：Testis specific.