Target：PDCD5

Gene Name：PDCD5 TFAR19

Protein Name：Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19)

Human Gene Id：9141

Human Swiss Prot No：O14737

Mouse Swiss Prot No：P56812

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：PDCD5 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：13kD

Background： This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010],

Function：developmental stage:Expression in fetal tissues is significantly lower than in adult tissues.,function:May function in the process of apoptosis.,induction:Activated in cells undergoing apoptosis.,similarity:Belongs to the PDCD5 family.,tissue specificity:Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.,

Subcellular Location：nucleus,cytoplasm,cytosol,extracellular exosome,

Expression：Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.