Target：PBF

Gene Name：PTTG1IP

Protein Name：Pituitary tumor-transforming gene 1 protein-interacting protein

Human Gene Id：754

Human Swiss Prot No：P53801

Mouse Gene Id：108705

Mouse Swiss Prot No：Q8R143

Rat Gene Id：365548

Rat Swiss Prot No：Q6P767

Immunogen：The antiserum was produced against synthesized peptide derived from human PTTG. AA range:116-165

Specificity：PBF Polyclonal Antibody detects endogenous levels of PBF protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PTTG1IP;C21orf1;C21orf3;Pituitary tumor-transforming gene 1 protein-interacting protein;Pituitary tumor-transforming gene protein-binding factor;PBF;PTTG-binding factor

Observed Band(KD)：20kD

Background： This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013],

Function：function:May facilitate PTTG1 nuclear translocation.,induction:By transcription factor RUNX2.,subcellular location:According to PubMed:10781616 it is found in the cytoplasm and the nucleus.,subunit:Interacts with PTTG1.,tissue specificity:Ubiquitous.,

Subcellular Location：Membrane ; Single-pass type I membrane protein . Cytoplasm . Nucleus . According to PubMed:10781616, it is found in the cytoplasm and the nucleus.

Expression：Ubiquitous.