Target:PGRC1
Gene Name:PGRMC1 HPR6.6 PGRMC
Protein Name:Membrane-associated progesterone receptor component 1 (mPR)
Human Gene Id:10857
Human Swiss Prot No:O00264
Mouse Swiss Prot No:O55022
Rat Swiss Prot No:P70580
Immunogen:Synthesized peptide derived from human protein . at AA range: 20-100
Specificity:PGRC1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):21kD
Background: This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010],
Function:domain:The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131.,function:Receptor for progesterone.,similarity:Belongs to the cytochrome b5 family. MAPR subfamily.,similarity:Contains 1 cytochrome b5 heme-binding domain.,tissue specificity:Widely expressed, with highest expression in liver and kidney.,
Subcellular Location:Microsome membrane ; Single-pass membrane protein . Smooth endoplasmic reticulum membrane ; Single-pass membrane protein . Mitochondrion outer membrane ; Single-pass membrane protein ; Extracellular side .
Expression:Widely expressed, with highest expression in liver and kidney. Expressed by endometrial glands and stroma (at protein level) (PubMed:23793472).