Target：PGK2

Fields：Glycolysis / Gluconeogenesis;Metabolic pathways;Carbon metabolism;Biosynthesis of amino acids;HIF-1 signaling pathway

Gene Name：PGK2 PGKB

Protein Name：Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific)

Human Gene Id：5232

Human Swiss Prot No：P07205

Mouse Swiss Prot No：P09041

Immunogen：Synthesized peptide derived from human protein . at AA range: 80-160

Specificity：PGK2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：45kD

Background：phosphoglycerate kinase 2(PGK2) Homo sapiens This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.[provided by RefSeq, May 2010],

Function：catalytic activity:ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.,online information:Phosphoglycerate kinase entry,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.,similarity:Belongs to the phosphoglycerate kinase family.,subunit:Monomer.,tissue specificity:Testis specific.,

Subcellular Location：Cytoplasm .

Expression：Mainly found in round spermatids. Localized on the principle piece in the sperm (at protein level). Testis-specific. Expression significantly decreased in the testis of elderly men.