Target:PF2R
Fields:Calcium signaling pathway;Phospholipase D signaling pathway;Neuroactive ligand-receptor interaction
Gene Name:PTGFR
Protein Name:Prostaglandin F2-alpha receptor (PGF receptor) (PGF2-alpha receptor) (Prostanoid FP receptor)
Human Gene Id:5737
Human Swiss Prot No:P43088
Mouse Swiss Prot No:P43117
Rat Swiss Prot No:P43118
Immunogen:Synthesized peptide derived from human protein . at AA range: 40-120
Specificity:PF2R Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):39kD
Background:prostaglandin F receptor(PTGFR) Homo sapiens The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function:function:Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Location:Cell membrane; Multi-pass membrane protein.
Expression:Eye.