Target:FTβ
Fields:Terpenoid backbone biosynthesis
Gene Name:FNTB
Protein Name:Protein farnesyltransferase subunit beta
Human Gene Id:2342
Human Swiss Prot No:P49356
Mouse Gene Id:110606
Mouse Swiss Prot No:Q8K2I1
Rat Gene Id:64511
Rat Swiss Prot No:Q02293
Immunogen:The antiserum was produced against synthesized peptide derived from human FNTB. AA range:255-304
Specificity:FTβ Polyclonal Antibody detects endogenous levels of FTβ protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:FNTB;Protein farnesyltransferase subunit beta;FTase-beta;CAAX farnesyltransferase subunit beta;Ras proteins prenyltransferase subunit beta
Observed Band(KD):49kD
Background:catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit.,
Function:catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit.,
Subcellular Location:cytosol,microtubule associated complex,protein farnesyltransferase complex,
Expression: Neuroblastoma,Placenta,Retina,