Target：PIG-H
Fields：Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;Metabolic pathways
Gene Name：PIGH
Protein Name：Phosphatidylinositol N-acetylglucosaminyltransferase subunit H
Human Gene Id：5283
Human Swiss Prot No：Q14442
Mouse Gene Id：110417
Mouse Swiss Prot No：Q5M9N4
Immunogen：The antiserum was produced against synthesized peptide derived from human PIGH. AA range:137-186
Specificity：PIG-H Polyclonal Antibody detects endogenous levels of PIG-H protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：PIGH;Phosphatidylinositol N-acetylglucosaminyltransferase subunit H;Phosphatidylinositol-glycan biosynthesis class H protein;PIG-H
Molecular Weight(Da)：21kD
Background： This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008],
Function：catalytic activity:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.,function:Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.,online information:Phosphatidylinositol N-acetylglucosaminyltransferase subunit H,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGH family.,subunit:Associates with PIGA, PIGC, PIGP, PIGQ and DPM2. The latter is not essential for activity.,
Subcellular Location：Cytoplasm.
Expression： Blood,Lung,Placenta,
