Target:PHAPI2
Gene Name:ANP32B
Protein Name:Acidic leucine-rich nuclear phosphoprotein 32 family member B
Human Gene Id:10541
Human Swiss Prot No:Q92688
Mouse Gene Id:67628
Mouse Swiss Prot No:Q9EST5
Rat Gene Id:170724
Rat Swiss Prot No:Q9EST6
Immunogen:The antiserum was produced against synthesized peptide derived from human ANP32B. AA range:1-50
Specificity:PHAPI2 Polyclonal Antibody detects endogenous levels of PHAPI2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:ANP32B;APRIL;PHAPI2;Acidic leucine-rich nuclear phosphoprotein 32 family member B;Acidic protein rich in leucines;Putative HLA-DR-associated protein I-2;PHAPI2;Silver-stainable protein SSP29
Observed Band(KD):29kD
Background:function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,
Function:function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity.,similarity:Belongs to the ANP32 family.,similarity:Contains 4 LRR (leucine-rich) repeats.,subcellular location:Accumulates in the nuclei at the S phase.,tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.,
Subcellular Location:[Isoform 1]: Nucleus . Cytoplasm . Accumulates in the nuclei at the S phase. .; [Isoform 2]: Cytoplasm. Lacks a nuclear localization signal.
Expression:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.