Target：PRX1

Gene Name：PRRX1

Protein Name：Paired mesoderm homeobox protein 1

Human Gene Id：5396

Human Swiss Prot No：P54821

Mouse Gene Id：18933

Mouse Swiss Prot No：P63013

Rat Gene Id：266813

Rat Swiss Prot No：P63014

Immunogen：Synthesized peptide derived from PRX1 . at AA range: 30-110

Specificity：PRX1 Polyclonal Antibody detects endogenous levels of PRX1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PRRX1;PMX1;Paired mesoderm homeobox protein 1;Homeobox protein PHOX1;Paired-related homeobox protein 1;PRX-1

Observed Band(KD)：27kD

Background： The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008],

Function：function:Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,

Subcellular Location：Nucleus.