Target：Peripherin

Fields：Amyotrophic lateral sclerosis;Pathways of neurodegeneration - multiple diseases

Gene Name：PRPH

Protein Name：Peripherin

Human Gene Id：5630

Human Swiss Prot No：P41219

Mouse Swiss Prot No：P15331

Rat Swiss Prot No：P21807

Immunogen：The antiserum was produced against synthesized peptide derived from human Peripherin. AA range:421-470

Specificity：PRPH Polyclonal Antibody detects endogenous levels of PRPH protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PRPH;NEF4;PRPH1;Peripherin;Neurofilament 4

Observed Band(KD)：55kD

Background： This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008],

Function：function:Class-III neuronal intermediate filament protein.,online information:Peripherin entry,similarity:Belongs to the intermediate filament family.,

Subcellular Location：Cytoplasm, cytoskeleton . Cell projection, axon . Perikaryon .

Expression：Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells.