Target：Prefoldin 1

Gene Name：PFDN1

Protein Name：Prefoldin subunit 1

Human Gene Id：5201

Human Swiss Prot No：O60925

Mouse Swiss Prot No：Q9CWM4

Immunogen：The antiserum was produced against synthesized peptide derived from human PFDN1. AA range:1-50

Specificity：Prefoldin 1 Polyclonal Antibody detects endogenous levels of Prefoldin 1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：PFDN1;PFD1;Prefoldin subunit 1

Observed Band(KD)：14kD

Background： This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008],

Function：function:Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.,similarity:Belongs to the prefoldin subunit beta family.,subunit:Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.,

Subcellular Location：prefoldin complex,

Expression： Colon,Thymus,