Target：PPR1A
Fields：Adrenergic signaling in cardiomyocytes;Long-term potentiation
Gene Name：PPP1R1A IPP1
Protein Name：Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) (I-1) (IPP-1)
Human Gene Id：5502
Human Swiss Prot No：Q13522
Mouse Swiss Prot No：Q9ERT9
Rat Swiss Prot No：P19103
Immunogen：Synthesized peptide derived from human protein . at AA range: 40-120
Specificity：PPR1A Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：18kD
Background：function:Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.,PTM:Phosphorylation of Thr-35 is required for activity.,similarity:Belongs to the protein phosphatase inhibitor 1 family.,subunit:Interacts with PPP1R15A.,
Function：function:Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.,PTM:Phosphorylation of Thr-35 is required for activity.,similarity:Belongs to the protein phosphatase inhibitor 1 family.,subunit:Interacts with PPP1R15A.,
Subcellular Location：extracellular space,cytoplasm,
Expression： Brain,Heart,
