Target：PPME1

Gene Name：PPME1 PME1 PP2593 PRO0750

Protein Name：Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89)

Human Gene Id：51400

Human Swiss Prot No：Q9Y570

Mouse Swiss Prot No：Q8BVQ5

Rat Swiss Prot No：Q4FZT2

Immunogen：Synthesized peptide derived from human protein . at AA range: 220-300

Specificity：PPME1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：42kD

Background： This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],

Function：function:Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro).,sequence caution:Wrong choice of CDS.,similarity:Belongs to the AB hydrolase superfamily.,subunit:Binds PPP2CB.,

Subcellular Location：cell-cell adherens junction,

Expression： Amygdala,Cervix carcinoma,Fetal liver,Lung,Platelet,Skin,