Target:RGS21
Gene Name:RGS21
Protein Name:Regulator of G-protein signaling 21 (RGS21)
Human Gene Id:431704
Human Swiss Prot No:Q2M5E4
Immunogen:Synthesized peptide derived from human protein . at AA range: 10-90
Specificity:RGS21 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):16kD
Background: Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM, Nov 2008],
Function:function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.,similarity:Contains 1 RGS domain.,tissue specificity:Expressed ubiquitously.,
Subcellular Location:cytoplasm,plasma membrane,
Expression:Expressed ubiquitously.