Target:Rab 31
Fields:Endocytosis
Gene Name:RAB31
Protein Name:Ras-related protein Rab-31
Human Gene Id:11031
Human Swiss Prot No:Q13636
Mouse Gene Id:106572
Mouse Swiss Prot No:Q921E2
Rat Gene Id:246324
Rat Swiss Prot No:Q6GQP4
Immunogen:Synthesized peptide derived from Rab 31 . at AA range: 50-130
Specificity:Rab 31 Polyclonal Antibody detects endogenous levels of Rab 31 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RAB31;RAB22B;Ras-related protein Rab-31;Ras-related protein Rab-22B
Observed Band(KD):21kD
Background: Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting (Bao et al., 2002 [PubMed 11784320]).[supplied by OMIM, Jul 2009],
Function:similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.,
Subcellular Location:Golgi apparatus, trans-Golgi network . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Rapidly recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
Expression:Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.