Target：PTPRG

Gene Name：PTPRG PTPG

Protein Name：Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48)

Human Gene Id：5793

Human Swiss Prot No：P23470

Mouse Swiss Prot No：Q05909

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：PTPRG Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：158kD

Background： The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008],

Function：catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,similarity:Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.,similarity:Contains 1 alpha-carbonic anhydrase domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 2 tyrosine-protein phosphatase domains.,tissue specificity:Found in a variety of tissues.,

Subcellular Location：Membrane ; Single-pass type I membrane protein .

Expression：Found in a variety of tissues.